Anti-Aging Articles

ANTI-AGING INGREDIENTS ON THE DINNER PLATE

We now we have some proof the anti-aging ingredients are on your dinner plate.  Researchers at McMaster University have developed a cocktail of ingredients that forestalls major aspects of aging.

FINDINGS

The findings are published in the current issue of Experimental Biology and Medicine.

The study found that a complex dietary supplement powerfully offsets this key symptom of ageing in old mice by increasing the activity of the cellular furnaces that supply energy – or mitochondria – and by reducing emissions from these furnaces – or free radicals – that are thought to be the basic cause of ageing itself.

Using bagel bits soaked in the supplement to ensure consistent and accurate dosing, the formula maintained youthful levels of locomotor activity into old age whereas old mice that were not given the supplement showed a 50 per cent loss in daily movement, a similar dramatic loss in the activity of the cellular furnaces that make our energy, and declines in brain signaling chemicals relevant to locomotion. This builds on the team’s findings that the supplement extends longevity, prevents cognitive declines, and protects mice from radiation.

Ingredients consists of items that were purchased in local stores selling vitamin and health supplements for people, including vitamins B1, C, D, E, acetylsalicylic acid, beta carotene, folic acid, garlic, ginger root, ginkgo biloba, ginseng, green tea extract, magnesium, melatonin, potassium, cod liver oil, and flax seed oil. Multiple ingredients were combined based on their ability to offset five mechanisms involved in ageing.

SCIENCE VS. NATURE

This study showed  both the remarkable extension of physical function in old mice, and extended longevity. With this comes hopes of developing more effective supplements.

Nature has already done that for us all we have to do is part take. What you put on your plate is more powerful than any supplements you buy.

It is a fact that lifestyle not genes predict aging.

British Heart Foundation Professor of Cardiology at the University of Leicester Professor Nilesh Samani, of the Department of Cardiovascular Sciences, who co-led the project explained that there are two forms of ageing – chronological aging i.e. how old you are in years and biological ageing whereby the cells of some individuals are older (or younger) than suggested by their actual age.

He said: “There is accumulating evidence that the risk of age-associated diseases including heart disease and some types of cancers are more closely related to biological rather than chronological age.

Aging

All of us age at different rates, and yes some people seem to age better. That is usually attributed to good genes. While that is not entirely wrong, there are a few factors to consider. Genes are turned on and off by lifestyle factors. Entering the world with good genes is nothing to sneeze at. Everyone, would like to be blessed with good genes.

However, the expression of these genes can be turned on or off by the way one lives. Chronological aging and biological aging can be on two different clocks. Age associated-diseases conditions are more closely related to biological aging than chronological.

Telomere Length

Individuals are born with telomeres of a certain length and in numerous cells telomeres become shorter as the cell divide and age. Telomere length is a marker for biological ageing.

The results of a recent study in JAMA suggested a link between inactivity and aging. They found the telomere length of individuals exercising with moderate to high intensity workouts of 199 plus minutes per week had telomere length of individuals 10 years younger than their sedentary counterpart.

Biological age should be lower then one’s chronological age.

Use It or Lose It

Use it or lose it has relevance in this study. Since diet and exercise are ways to stay biologically young, than taking care is survival 101. Genes aren’t your destiny. Your outlook, diet, and exercise routines may be the most important components in increasing both the length and quality of your life.

Finding the overeating triggers and dangers in our culture is simple. All you have to do is follow the advertising and obesity rates. The food industry represents a threat that is as big as any to our society. The reason; there is no place to hide from either the advertisements, or the available supply. They know the pathway to desire. Their campaigns are hardcore. They build it and see that you use it. They know most people will surrender to desire.

Dangers 

It has been found that overeating in mice triggers a molecule that destroys metabolism. This also leads to resistance and sets the stage for type 2 diabetes.

This is a new study, by researchers at the Harvard School of Public Health (HSPH) that links together the immune system and metabolism. These are paired together as suspect in increasing diseases from diabetes, heart disease, fatty liver, cancer and stroke.  

Science

“When mice eat a normal diet, this molecule called PKR is silent,” states senior author Gokhan Hotamisligil, chair of the HSPH department of Genetics and Complex Disease. “However, if a cell containing PKR is bombarded with too many nutrients, PKR grabs other immune system molecules that respond to this food attack and organizes a firing squad to shoot down normal processes, leading to insulin resistance and metabolic dysfunction.”

“We know that nutrients can be detrimental in excess quantities or when they are in the wrong place at the wrong time,” Hotamisligil said. “But we don’t quite understand which paths they travel that result in harm and produce inflammation. PKU is a mechanism by which nutrients-necessary and beneficial under normal conditions-cause damage to cells and organs.”

PKR stands for Protein Knase R. Protein Knases have a profound effect on cells.

Protein Kinases are key regulators of cell function that constitute one of the largest and most functionally diverse gene families. They orchestrate the activity of almost all cellular processes.

The results provide compelling evidence that a process called “metaflammation” occurs in the body, stated Hotamisligil. Metaflammation is inflammation that occurs while the body processes food into energy. Hotamisligi had demonstrated inflammation role in metabolic diseases such as type 2 diabetes, and heart disease in mice and humans.

Metaflammation describes ailments resulting from an unhealthy lifestyle.The two main causes are a lack of nutrition and a lack of exercise. Overeating is a way to use and deplete nutrients.

Reality

Researches are looking to understand how to regulate the PKR molecule through targeted drugs or nutrients. They think this could be the way diseases are prevented and treated in humans. We build, than battle what we build. Having build up a surreal supply of faux foods, we now have to subdue its effect on us.

We are not doomed to a roller coster existence. This is one where we produce new foods and then need drugs to modify the effect. We are at a crossroad in scientific thinking. We are spawning a dangerous trend; lifestyles that depend on technology may be in for some eye-opening surprise.

Conclusion

The causes of many of the diseases appear to lie in aspects of our modern technology driven environment. This is the red light district, where there is real danger of picking up a life threatening illness.

It’s Not Your Fault-Why you Overeat- Presented by Dr.David Kessler a former commissioner of The Food and Drug Administration (FDA).