Posts Tagged ‘dr. david kessler’

Finding the overeating triggers and dangers in our culture is simple. All you have to do is follow the advertising and obesity rates. The food industry represents a threat that is as big as any to our society. The reason; there is no place to hide from either the advertisements, or the available supply. They know the pathway to desire. Their campaigns are hardcore. They build it and see that you use it. They know most people will surrender to desire.

Dangers 

It has been found that overeating in mice triggers a molecule that destroys metabolism. This also leads to resistance and sets the stage for type 2 diabetes.

This is a new study, by researchers at the Harvard School of Public Health (HSPH) that links together the immune system and metabolism. These are paired together as suspect in increasing diseases from diabetes, heart disease, fatty liver, cancer and stroke.  

Science

“When mice eat a normal diet, this molecule called PKR is silent,” states senior author Gokhan Hotamisligil, chair of the HSPH department of Genetics and Complex Disease. “However, if a cell containing PKR is bombarded with too many nutrients, PKR grabs other immune system molecules that respond to this food attack and organizes a firing squad to shoot down normal processes, leading to insulin resistance and metabolic dysfunction.”

“We know that nutrients can be detrimental in excess quantities or when they are in the wrong place at the wrong time,” Hotamisligil said. “But we don’t quite understand which paths they travel that result in harm and produce inflammation. PKU is a mechanism by which nutrients-necessary and beneficial under normal conditions-cause damage to cells and organs.”

PKR stands for Protein Knase R. Protein Knases have a profound effect on cells.

Protein Kinases are key regulators of cell function that constitute one of the largest and most functionally diverse gene families. They orchestrate the activity of almost all cellular processes.

The results provide compelling evidence that a process called “metaflammation” occurs in the body, stated Hotamisligil. Metaflammation is inflammation that occurs while the body processes food into energy. Hotamisligi had demonstrated inflammation role in metabolic diseases such as type 2 diabetes, and heart disease in mice and humans.

Metaflammation describes ailments resulting from an unhealthy lifestyle.The two main causes are a lack of nutrition and a lack of exercise. Overeating is a way to use and deplete nutrients.

Reality

Researches are looking to understand how to regulate the PKR molecule through targeted drugs or nutrients. They think this could be the way diseases are prevented and treated in humans. We build, than battle what we build. Having build up a surreal supply of faux foods, we now have to subdue its effect on us.

We are not doomed to a roller coster existence. This is one where we produce new foods and then need drugs to modify the effect. We are at a crossroad in scientific thinking. We are spawning a dangerous trend; lifestyles that depend on technology may be in for some eye-opening surprise.

Conclusion

The causes of many of the diseases appear to lie in aspects of our modern technology driven environment. This is the red light district, where there is real danger of picking up a life threatening illness.

It’s Not Your Fault-Why you Overeat- Presented by Dr.David Kessler a former commissioner of The Food and Drug Administration (FDA).