Posts Tagged ‘glucose’

Diabetes- the clue to cancer is not as strange as it sounds.

Glucose Connection               

The diabetes glucose connection is well known.

What is less known is that cancer cells grow so fast that they can become short of oxygen. They outstrip their blood supply; this is how oxygen is delivered. The cells then produce energy that needs less oxygen but more sugar.

Researches at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have designed an experimental drug that chokes off that sugar supply, causing the cells to self destruct.

The agent, called OSU-CG12K is an example of a new class of anticancer drugs energy-restrictive mimetic agents. It is described in a paper published recently in the Journal of Biological Chemistry.

“Our study proves that this new agent kills cancer cells through energy restriction. This is important because it shows that it is possible to design drugs that target energy restriction, and it is exciting because energy-restricting mimetic agents may also be useful for other diseases, including metabolic syndromes, diabetes, cardiovascular disease and obesity,” chen said.

Energy-restricting mimetic agents cause changes in cancer cells that are similar to those that occur in can cells deprived of their main energy source, the sugar glucose.

Diabetes Sugar Connection

Most people are aware there is a diabetes sugar connection. Also, most are informed enough to know simple carbohydrates are going to cause problems.

What isn’t as well understood is that the same dietary solutions applied to cancer will have an effect.

Scientist at Umea University in Sweden funded by the World Cancer Research Fund (WCRF), examined blood sugar levels in 274,126 men and 275,818 women from Norway, Austria and Sweden with an average age of 44.8, than followed them for a decade.

They wrote: “Significant increases in risk among men were found for incident and fatal cancer of the liver, gallbladder, and respiratory tract, for incident thyroid cancer and multiple myeloma, and for fatal rectal cancer. In women, significant associations were found for incident and fatal cancer of the pancreas, for incident urinary bladder cancer, and for fatal cancer of the uterine corpus, cervix uteri and stomach.”

Glucose

Glucose is the common denominator for both diabetes and cancer. The alternative practitioners have been saying for years sugar feeds cancer. They were correct.  Most of the medical community have been saying up to now, that diet has little to do with this condition.

Calorie restriction along with a nutrient dense diet is promoted by many alternative health care practitioners. Both a low sugar and lower calorie diet have been promoted as a preventative method and a way to reverse most conditions.

The benefits of a low sugar, and a low calorie diet when applied correctly will prevent and ameliorate these conditions. Your body will do the healing if given the tools.

There is perception that there isn’t enough evidence to prove that a sugar high-sugar additction is real. There are many dimensions to the sugar high-sugar addiction phenomenon that is sweeping the country.

From Wiki Online

“A sugar “high” occurs when your bloodstream is flooded with glucose, usually produced from ingested carbohydrates which can easily be converted into glucose, such as sugars and certain polymers of sugar, such as starches. Your brain is unique in that it requires glucose, and cannot use other forms of energy such as fats or proteins. So when glucose levels are high in your blood, you feel energized and awake. The state of high blood-glucose levels, through a very fundamental signaling system, triggers the release of insulin from cells in your pancreas. Insulin is a directive for your body to store this extra energy as fat once your glycogen reserve has been topped off (so you can make it through the winter and other times when there may be no food). Therefore, your entire body feels active during a sugar high.”

Sugar Rollercoaster

“On the other hand, a sugar “crash” is probably on the way. If a very large amount of easily broken down carbohydrates is ingested, blood-glucose levels rise rapidly and cause a high degree of insulin release. This creates a sugar “rollercoaster” inside your body as glucose levels are brought down precipitously, to the point where you feel fatigued, tired, and…hungry! Eventually, your body can become resistant to insulin, causing chronic high blood-glucose levels. This is known as hyperglycemia, and is the beginning stage of type II diabetes.”

Craving Sugar

There is such a thing as a sugar high. Also, sugar craving seems to be something that occurs in industrialized societies. This is different than just liking the taste of sweet foods one in awhile.

This is part and parcel of the American Standard Diet. An acronym is the (SAD) diet. That may as well stand for the sugar addiction diet, of the salt addiction diet. Both of these hold true, as all food manufacturing companies understand so well.

Sugar Addiction

Is there such a thing as a recovered sugar addict? This is different that a recovering alcoholic or drug user. Most of our current food supply contains sugar or a sugar substitute. Any sugar substitute sets you up to crave more sweets. 

You can keep a sugar addiction by consuming better forms, such as a high fruit diet. That may not cut it for a true sugar addict. It is a fact that many Americans are addicted to this substance. Without being aware of the reasons for their food preferences, such as pancakes, coffee with sugar, sweet cereals, nearly all restaurant foods have some sugar as an ingredient.

The average American consumes 2-3 pounds of sugar a week. This includes all forms from sucrose (table sugar), dextrose (corn sugar) and high-fructose corn syrup. High fructose corn syrup is in many processed foods. These include bread, cereal, mayonnaise, peanut butter, ketchup, spaghetti sauce, and most pre-packaged foods.

Wikipedia on Sugar Addiction

There has been reference to the idea of sugar addiction in the popular literature for a number of years.

In 1998, Kathleen DesMaisons outlined the concept of sugar addiction as a measurable physiological state caused by activation of mu-opioid receptors in the brain. Her work extracted data from studies done showing that sugar acted as an analgesic drug whose effects could be blocked by a morphine blocker.

“Recent behavioral tests in rats further back the idea of an overlap between sweets and drugs. Drug addiction often includes three steps.

A person will increase his intake of the drug, experience withdrawal symptoms when access to the drug is cut off and then face an urge to relapse back into drug use.

Rats on sugar have similar experiences. Researchers withheld food for 12 hours and then gave rats food plus sugar water. This created a cycle of binging where the animals increased their daily sugar intake until it doubled. When researchers either stopped the diet or administered an opioid blocker the rats showed signs common to drug withdrawal, such as teeth-chattering and the shakes.

Early findings also indicate signs of relapse. Rats weaned off sugar repeatedly pressed a lever that previously dispensed the sweet solution.”(Leah Ariniello, Brain Briefings, October 2003)

For years allopathic medicine said it’s in the genes, and nutrition had nothing to do with your condition. What a relief for most people they could keep doing what they always did. However, what was left out was if you keep doing what you always do you will keep getting the same results. Holistic healing modalities recognizes that the path to health in not in the pill bottles lining your medicine cabinet.

It has been found that the best strategy for a long life free of debilitating disease would be to restrict calories. The best way to do that is to cut down on glucose. This is what helps human cells live longer. This discovery was published in the FASEB Journal (Federation of American Societies for Experimental Biology). 

Changes

This is the reaction that I would expect to the news. Changes that get you moving in the right direction include weight control, and tweaks to your lifestyle. Understanding what getting healthier means, will help you makeover your health. This is holistic healing, and this is the future of medicine.

Believe it of Not

“Western science is on the cusp of developing a pharmaceutical fountain of youth” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “This study confirms that we are on the path to persuading human cells to let us to live longer, and perhaps cancer-free, lives.”

Don’t Hold Your Breath

“Our hope is that the discovery that reduced calories extends the lifespan of normal human cells will lead to further discoveries of the causes for these effects in different cell types and facilitate the development of novel approaches to extend the lifespan of humans,” said Trygve Tollefsbol, Ph.D., a researcher involved in the work from the Center for Aging and Comprehensive Cancer Center at the University of Alabama at Birmingham. “We would also hope for these studies to lead to improved prevention of cancer as well as many other age-related diseases through controlling calorie intake of specific cell types.”

The people that have been practicing this type of lifestyle have proved that this works without pharmacitical intervention. There is no need to wait for conclusive studies, the research studies are compelling, and the best proof is the success of the people that have benefited from this.

Calorie Poisoning

This is the malady that many people suffer from. When people hear calorie restriction they think starvation diet. Well most people are on a starvation diet. How could that be with all the abundance?

Nutrient starvation for lack of a better term means cells are starving and can’t function well. That is what happens when you consume calories from non-nutritious sources. The other problem is when the amount of food shoved in on a continuous basis is too large for the organs to handle you become toxic.

Once your cells are toxic they can’t perform their jobs very well. We are being calorie poisoned. Our systems never have a chance to rest between eating. Digestion takes a lot of energy, that can be used for repair work.

Where To Start

When your hear calorie restriction, think of it as the opposite of calorie poisoning. Restricting Glucose that is part of most packaged food is a good way to start. This sure beats waiting for drugs that will slow human aging and prevent cancer. The formula for doing that is on your dinner plate.

Starting this before another round of scientific studies is conducted would be prudent. After you start you will know the results in short order.

Alternative ways to health that are sensible have been known for centuries. In this decade we need researches to discover the obvious. How far we have come from common sense is due to the power of modern medicine.

Paul Nison Provides Proof