Toxicity-Pharmacology
Toxicity and pharmacology are words that are joined at the hip.
Pharmacology
Pharmacology is the study of drug action and the interaction on a biological system. When a substance has medical properties they are pharmaceuticals. This field looks at the drugs property, interactions, toxicology, and medical applications. The pharmacy side is expected to be concerned with both the safety and effective use of the product.
Drug Toxicity
Drug toxicity is tied to both drug metabolism, and interactions with other prescriptions. While the pharmaceutical industry is looking to build more profits, the arsenal of drugs keep growing.
Variety in most markets is considered good. The world of pharmaceuticals is a place where they are always brewing up a new formula. Most are equivalents of some rival manufacturer. Some of these products aren’t fully validated for safety, and with little or no study of how they interact with other agents.
Research led by Wayne L. Backes, PhD, professor of pharmacology and Associate Dean for Research at Louisiana State University (LSU) Health Sciences Center New Orleans School of Medicine, found that drug metabolism depends not only on which enzymes are present in an individual, but how they interact. This makes the difference in whether a drug can be safely eliminated from the body or is converted into a toxic carcinogenic byproduct. The paper is in the Journal of Biological Chemistry.
Dr. Backes and his research colleagues, J. Robert Reed PhD, Pharmacology Assistant Professor and Marylyn Ever, Research Associate have studied an enzyme called Cytochrome P450 which is responsible for the removal of the majority of drugs from the body by chemically breaking them down into inactive substances or metabolites. Because there are so many, there is a high degree of variability in people’s responses to a drug.
Pharmaceutical Companies
Pharmaceutical companies are on a roll. Today’s consumers want easy answers to their health problems. At the core of this are the consumer’s criteria for a healthy solution. From the prescription pad to the pharmacy the drug companies have the competitive edge.
They have the plum position of being able to control the studies, and the information that reaches the consumer. Not only can they influence and educate the doctors, they can advertise straight to the consumer.
Healthcare
Healthcare is on an incredible mission. They expect to medicate people into health. They may wipe out a symptom, without changing the condition. To me it is wheeling and dealing with the backing of the pharmaceutical industry. They change one thing and cause two things in exchange.
There are technical problems that are never addressed. How does taking 7 pills or more a day interact when given together? Since no one has tested this short or long term, detecting the changes should give every patient anxiety.
The confidence that the consumer seem to have in the medical system eludes me. Medication is not science, and every breakthrough proves that the conclusions may not be reliable. What is small, red and powerful, a raspberry or strawberry of course. However, if it is a contest with a little red pill, the drug would win hands down.
You can’t count on performance or value when you put your health in the hands of the pharmaceutical Industry.
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